Being of Spanish descent, Vega made her debut to television in the Spanish television series Menu es mi padre. She would later go on to star in two other Spanish television series in 1997: Mas que amigos and Companeros. While popular, these series did not help Vega's career much, with her finding success two years later in 1999; starring in 7 Vidas, which was dubbed as the Spanish version of the popular sitcom Friends.
Since her appearance in 7 Vidas, her career has grown exponentially, starring alongside some of the television/movie industries biggest stars, Adam Sandler, Morgan Freeman, Scarlett Johannson and Samuel L. Jackson.
She has alsop diversified her career, replacing Penelope Cruz as the face of L'Oreal Spain, following a signing with 1/One Management in New York.